Autoimmune diseases are a group of disorders in which the immune system mistakenly targets and attacks the body’s own tissues and organs. There are more than 80 recognized autoimmune diseases, and they can affect virtually any part of the body. Here is a list of some common autoimmune diseases:
Please note that this list is not exhaustive, and there are many other autoimmune diseases, each with its unique characteristics, symptoms, and treatment approaches. If you suspect you have an autoimmune condition or have been diagnosed with one, it’s essential to work closely with a healthcare professional for proper evaluation, diagnosis, and management.
Here are concise summaries for each of the listed autoimmune diseases:
- Rheumatoid Arthritis: A chronic autoimmune condition that primarily affects the joints, causing inflammation, pain, and potential joint damage.
- Systemic Lupus Erythematosus (SLE): A systemic autoimmune disease where the immune system attacks various body tissues, leading to inflammation and damage in organs like the skin, kidneys, and heart.
- Type 1 Diabetes: An autoimmune disease in which the immune system destroys insulin-producing cells in the pancreas, leading to high blood sugar levels.
- Multiple Sclerosis (MS): A neurological autoimmune disorder where the immune system attacks the protective covering of nerves, causing communication issues between the brain and the rest of the body.
- Hashimoto’s Thyroiditis: An autoimmune disorder in which the immune system attacks the thyroid gland, often leading to hypothyroidism.
- Graves’ Disease: An autoimmune condition where the immune system overstimulates the thyroid gland, resulting in hyperthyroidism.
- Celiac Disease: An autoimmune disorder triggered by gluten consumption, causing damage to the small intestine and leading to malabsorption of nutrients.
- Inflammatory Bowel Disease (IBD) – Crohn’s Disease and Ulcerative Colitis: Chronic inflammatory conditions of the gastrointestinal tract, with Crohn’s affecting any part of the GI tract and ulcerative colitis primarily impacting the colon and rectum.
- Psoriasis: A chronic autoimmune condition that speeds up the life cycle of skin cells, leading to thick, scaly patches of skin.
- Sjögren’s Syndrome: An autoimmune disease that primarily targets the glands that produce tears and saliva, leading to dry eyes and mouth.
- Vitiligo: An autoimmune condition where the immune system attacks melanocytes, causing loss of skin pigmentation in patches.
- Addison’s Disease: An autoimmune disorder where the immune system damages the adrenal glands, leading to insufficient production of certain hormones, particularly cortisol.
- Guillain-Barré Syndrome: A rare autoimmune disorder where the immune system attacks the peripheral nerves, leading to muscle weakness and paralysis.
- Myasthenia Gravis: A chronic autoimmune disorder that disrupts the communication between nerves and muscles, causing muscle weakness and fatigue.
- Ankylosing Spondylitis: A type of arthritis that primarily affects the spine, leading to inflammation, pain, and potentially the fusion of vertebrae.
- Polymyalgia Rheumatica: An inflammatory disorder causing muscle pain and stiffness, particularly in the shoulders and hips.
- Pernicious Anemia: An autoimmune condition that impairs the absorption of vitamin B12, leading to a decrease in red blood cell production.
- Antiphospholipid Syndrome: An autoimmune disorder that increases the risk of blood clots, leading to complications such as deep vein thrombosis or stroke.
- Scleroderma (Systemic Sclerosis): A rare autoimmune disease characterized by the hardening and tightening of the skin and connective tissues, and potentially affecting internal organs.
- Dermatomyositis: An autoimmune condition that causes muscle inflammation and skin rashes, often accompanied by muscle weakness.
- Polymyositis: A rare autoimmune disorder that causes chronic inflammation and weakness in the skeletal muscles.
- Autoimmune Hepatitis: A condition where the immune system attacks the liver, leading to inflammation and potential liver damage.
- Goodpasture Syndrome: A rare autoimmune disease where the immune system attacks the lungs and kidneys, leading to bleeding in the lungs and kidney failure.
- Pemphigus: A group of rare autoimmune blistering disorders that affect the skin and mucous membranes.
- Wegener’s Granulomatosis (Granulomatosis with Polyangiitis): A rare autoimmune condition that causes inflammation of the blood vessels, leading to damage in the respiratory tract and kidneys.
- Takayasu’s Arteritis: A rare autoimmune disease that causes inflammation of the large arteries, particularly the aorta and its branches.
- Giant Cell Arteritis (Temporal Arteritis): An autoimmune condition that causes inflammation of the arteries in the head, particularly the temples, potentially leading to vision loss.
- Behçet’s Disease: A rare autoimmune disorder that causes inflammation of blood vessels throughout the body, leading to mouth sores, genital ulcers, and eye inflammation.
- Polyarteritis Nodosa: A rare autoimmune disease that causes inflammation of the small and medium-sized arteries, leading to organ damage.
- Mixed Connective Tissue Disease: An autoimmune disorder that combines features of several connective tissue diseases, including lupus, scleroderma, and polymyositis.
- Idiopathic Thrombocytopenic Purpura (ITP): An autoimmune disorder where the immune system destroys platelets, leading to excessive bruising and bleeding.
- Eosinophilic Esophagitis (EoE): An allergic/autoimmune condition where eosinophils accumulate in the esophagus, leading to inflammation and difficulty swallowing.
- Primary Biliary Cholangitis (PBC): An autoimmune disease where the immune system slowly destroys the bile ducts in the liver, leading to liver damage.
- Primary Sclerosing Cholangitis (PSC): A rare autoimmune condition that causes inflammation and scarring of the bile ducts, leading to liver damage.
- Narcolepsy with Cataplexy: A neurological disorder that can have autoimmune origins, characterized by sudden muscle weakness (cataplexy) and excessive daytime sleepiness.
- Autoimmune Encephalitis: A group of disorders where the immune system attacks the brain, leading to inflammation and neurological symptoms.
- Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): A neurological disorder where the immune system attacks the peripheral nerves, causing weakness and sensory loss.
- Stiff Person Syndrome (SPS): A rare neurological disorder characterized by muscle stiffness and spasms, believed to be autoimmune in origin.
- Paraneoplastic Pemphigus: An autoimmune blistering disorder associated with certain cancers, leading to severe skin and mucous membrane damage.
- Autoimmune Hemolytic Anemia: A condition where the immune system destroys red blood cells, leading to anemia.
- Autoimmune Pancreatitis: A type of chronic pancreatitis where the immune system attacks the pancreas, leading to inflammation and potential organ damage.
- Mast Cell Activation Syndrome (MCAS): A disorder where mast cells are overly reactive, releasing excessive chemicals that cause chronic allergic-like symptoms.
- PANDAS/PANS: Autoimmune neuropsychiatric disorders in children triggered by streptococcal infections, leading to sudden onset of OCD and other psychiatric symptoms.
- Autoimmune Polyendocrine Syndromes (APS): A group of rare disorders where the immune system attacks multiple endocrine glands, leading to hormone imbalances.
- Autoimmune Inner Ear Disease (AIED): A condition where the immune system attacks the inner ear, causing hearing loss and balance issues.
- Complex Regional Pain Syndrome (CRPS): A chronic pain condition that can have an autoimmune component, causing severe pain, swelling, and changes in the skin.
- Chronic Fatigue Syndrome (CFS): A condition characterized by extreme fatigue that may have an autoimmune component, leading to long-lasting and debilitating symptoms.
- Autoimmune Urticaria (Chronic Hives): A condition where the immune system causes chronic hives and angioedema without a known trigger.
- Alopecia Areata: An autoimmune condition where the immune system attacks hair follicles, leading to patchy hair loss.
- Autoimmune Retinopathy: A rare autoimmune disorder where the immune system attacks the retina, leading to vision loss.
In the following articles we will address some of these illnesses.